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The scientists have successfully isolated the protein which can control the activation of brown fat in the brain and body tissue. Their findings are published in issue of the journal Cell on the 11th of May.
White fat is usually understood the tissue to store fat Dries Mertens World Cup Jersey , while brown fat (also known as brown adipose tissue) burns fat used in the process of heat (thermogenesis) to generate heat. Through research, scientists from the University of Cambridge Metabolic Research Laboratory discovered the unique role of protein BMP8B in the metabolic system (especially in the brain and surrounding tissue), making it a potential therapeutic target.
Scientists believe that by burning brown fat can help obese people complete weight loss programs, weight loss process is very difficult to complete with common sense.
Dr. Andrew Whittle, one of the authors of the article Divock Origi World Cup Jersey , told reporters: "other proteins produced by the body also can enhance brown fat calories, such as thyroid hormone. But these proteins also play an important role in other organs, they do not suitable as a weight loss therapy target. For now, BMP8B protein is only for control of brown fat calorie burning, which means that human’s intervention can become a new treatment.
The results show that they are difficult to maintain their normal body temperature and the more obese than normal mice Dedryck Boyata World Cup Jersey , when mice lack BMP8B protein.. Then the researchers use brown fat cells containing BMP8B protein injected into the surrounding tissue, brown fat’s reaction is very strong. The researchers further have BMP8B injection into the specific structure of the brain and it stimulates the process of activation of brown adipose tissue. The results showed that, using the the rich brown BMP8B fat cells can burn more fat. If the brain can be given, it can reduced weight significantly.
Professor Toni Vidal-Puig, the person in charge of the study Christian Kabasele World Cup Jersey , emphasized that "people by some means can alleviate a certain weight, but when the weight reaches a platform, it is difficult to decline continuously. Because the human body can base on changes in weight regulation of food consumption and metabolic efficiency in order to maintain a normal physiological processes. It can be used if the metabolic rate does not change. For the purpose of fat consumption, increasing brown adipose cells so as to achieve the purpose of weight loss. "
People often think that when increasing the metabolic rate of the body, it will increase the desire to eat to make up for the loss of high-energy metabolism. But this study shows the BMP8B does not produce a similar effect Christian Benteke World Cup Jersey , but simply by burning brown fat to achieve weight loss.

Alibaba Group Holding Ltd founder Jack Ma on Monday surprised potential investors at a standing-room only event in New York by addressing governance concerns over the Chinese e-commerce giant, including a controversial 2010 spin-off of its online payment service.

Ma made the remarks at a luncheon at the Waldorf Astoria hotel in New York in front of hundreds of hedge funds, mutual funds and other institutional investors, as the company kicked off a two-week, multi-city marketing blitz for its initial public offering.

Ma addresses investors at a luncheon at the Waldorf Astoria hotel in New York Ma addresses investors at a luncheon at the Waldorf Astoria hotel in New York Ma addresses investors at a luncheon at the Waldorf Astoria hotel in New York Ma addresses investors at a luncheon at the Waldorf Astoria hotel in New York

Alibaba was expecting about 500 investors to attend the first stop on the roadshow Axel Witsel World Cup Jersey , but some 800 showed up, forcing some into overflow rooms.

Alibaba is seeking to raise more than $21 billion in the largest-ever U.S. technology IPO, valuing the company at up to $163 billion. It expects to price the IPO at $60 to $66 per American Depositary Share, which are scheduled to start trading on the New York Stock Exchange later this month.

Industry analysts had expected Alibaba to try for a valuation in excess of $200 billion, ranking it among the 20 largest publicly traded companies in the United States. The marketing effort Zakaria Bakkali Jersey , which will take Alibaba on a globe-trotting tour, will help determine whether the company will price above its initial range and come closer to that valuation.

Several investors who spoke with Reuters before and after the event said they went into the presentation with a series of questions about Alibaba, ranging from concerns about its corporate governance and transparency, to plans for U.S. acquisitions and growth. They said they did not learn anything new during the lunch - of boxed turkey sandwiches - but came away feeling the event was well-choreographed.

Akram Yosri, a managing partner at 3iCapital Group Yannick Carrasco Belgium Jersey , said he had hoped to find out more about how the company planned to grow globally, and particularly how it plans to compete with Amazon Inc (AMZN.O) and eBay Inc (EBAY.O) in the United States.

"Did I learn anything? Absolutely not," he said.

But Yosri and other investors said they found Ma to be impressive, with some describing the former English teacher who founded the company in his apartment as "charismatic". In his 10-minute remarks, Ma emphasized how the company serves small businesses in China and addressed issues of governance Toby Alderweireld Belgium Jersey , investors said.

Alibaba accounts for about 80 percent of all online retail sales in China, where rising Internet usage and an expanding middle class helped the company generate gross merchandise volume of $296 billion in the 12 months ended June 30. Revenue in the June quarter increased 46 percent to $2.54 billion from a year earlier, faster than the 38.7 percent growth in the previous quarter.

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